Ramiprilat Diketopiperazine(Mixture of Diastereoisomers)

CAS: 108736-10-3

Ref. TR-R111030

Product Information

• Name: Ramiprilat Diketopiperazine(Mixture of Diastereoisomers)
• Synonyms: Ramipril Diketopiperazine Acid, Ramipril Imp. K (EP),(2S)-2-[(3S,5aS,8aS,9aS)-3-methyl-1,4-dioxodecahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl]-4-phenylbutanoic acid, (alphaS,3S,5aS,8aS,9aS)-Decahydro-3-methyl-1,4-dioxo-alpha-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic Acid, 2H-Cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic acid, decahydro-3-methyl-1,4-dioxo-alpha-(2-phenylethyl)-, [3S-[2(R*),3alpha,5abeta,8abeta,9abeta]]- (9CI), (alphaS,3S,5aS,8aS,9aS)-Decahydro-3-methyl-1,4-dioxo-alpha-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic acid, Ramipril Impurity K, [3S-[2(R*),3a,5ab,8ab,9ab]]-Decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic Acid, [3S-[2(R*),3a,5a,8a,9a]]-Decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic Acid

Description

Impurity Ramipril EP Impurity K
Applications Ramiprilat Diketopiperazine (Mixture of Diastereoisomers) (Ramipril EP Impurity K) is a metabolite of Ramipril (R111000).
References Tabata, S., et al.: J. Biopharm. Sci., 1, 235 (1990),

• Brand: TRC

Chemical properties

• Molecular weight: 370.44
• Formula: C₂₁H₂₆N₂O₄
• Color/Form: White To Off-White
• InChI: InChI=1S/C21H26N2O4/c1-13-19(24)23-16-9-5-8-15(16)12-18(23)20(25)22(13)17(21(26)27)11-10-14-6-3-2-4-7-14/h2-4,6-7,13,15-18H,5,8-12H2,1H3,(H,26,27)/t13-,15-,16-,17-,18-/m0/s1
• InChI key: InChIKey=DZRWPCCIYKIPJW-VYAKSYEXSA-N
• SMILES: C[C@H]1C(=O)N2C(C[C@@H]3CCC[C@@H]32)C(=O)N1C(CCc1ccccc1)C(=O)O