Estimated delivery in United States, on Tuesday 23 Jul 2024
Product Information
Name:
Regorafenib N-b-D-Glucuronide Sodium Salt
Controlled Product
Synonyms:
- (2S,3S,4S,5R,6R)-6-(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)ureido)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid Sodium Salt
- 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-
- 4-[4-[N′-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic acid methylamide
- 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide
- Bay 73-4506
- Regorafenib
- Stivarga
CAS:
Description:
Applications Regorafenib N-β-D-Glucuronide Sodium Salt, is a derivative of Regorafenib (R143000); a compound that inhibits PDGFR tyrosine kinase with IC50=83nM. Also useful for the treatment of inflammation and as an anti-proliferative agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
680.92
Formula:
C27H22ClF4N4NaO9
Color/Form:
Neat
InChI:
InChI=1S/C27H23ClF4N4O9.Na/c1-33-23(40)18-10-13(6-7-34-18)44-12-3-5-17(16(29)9-12)35-26(43)36(11-2-4-15(28)14(8-11)27(30,31)32)24-21(39)19(37)20(38)22(45-24)25(41)42;/h2-10,19-22,24,37-39H,1H3,(H,33,40)(H,35,43)(H,41,42);/q;+1/p-1/t19-,20-,21+,22-,24+;/m0./s1
InChI key:
InChIKey=AWDORCFLUJZUQS-CYBMUJFWSA-N
SMILES:
Cc1cncc2cccc(S(=O)(=O)N3CCCNC[C@H]3C)c12
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-R143320 Regorafenib N-b-D-Glucuronide Sodium Salt
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