Resiquimod

CAS: 144875-48-9

Ref. TR-R144680

Product Information

• Name: Resiquimod
• Synonyms: 1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol, 4-Amino-2-(ethoxymethyl)-1-(2-hydroxyisobutyl)imidazo[4,5-c]quinoline, 4-Amino-2-ethoxymethyl-a,a-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol, R 848, S 28463, 1-[4-Amino-2-(ethoxymethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol, 1H-Imidazo[4,5-c]quinoline-1-ethanol, 4-amino-2-(ethoxymethyl)-α,α-dimethyl-, 4-Amino-2-(ethoxymethyl)-alpha,alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol, 4-Amino-2-(ethoxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol, R-848, Resimiquimod, S-28463, Vml-600
• CAS: 144875-48-9

Description

Applications Resiquimod is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.
References Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008);

• Brand: TRC

Chemical properties

• Molecular weight: 314.38
• Formula: C₁₇H₂₂N₄O₂
• Color/Form: White Solid
• InChI: InChI=1S/C17H22N4O2/c1-4-23-9-13-20-14-15(21(13)10-17(2,3)22)11-7-5-6-8-12(11)19-16(14)18/h5-8,22H,4,9-10H2,1-3H3,(H2,18,19)
• InChI key: InChIKey=FHJATBIERQTCTN-UHFFFAOYSA-N
• SMILES: CCNCc1nc2c(=N)[nH]c3ccccc3c2n1CC(C)(C)O