13-cis-Retinoic Acid

CAS: 4759-48-2

Ref. TR-R250000

Product Information

• Name: 13-cis-Retinoic Acid
• Synonyms: Isotretinoin, (2Z,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenoic acid, Retinoic acid, 13-cis-, (13Z)-Retinoic acid, 13-RA, 13-cis-Vitamin A acid, 13-cis-ß-Retinoic acid, AGN 190013, Accure, Accutane, Isotrex, IsotrexGel, Neovitamin A acid, Ro 4-3780, Roaccutan, Roaccutane, cis-Retinoic acid, (13Cis)-15-Oxidoretinal, 13-Cis-Retinoic Acid, 13-Cis-Vitamin A Acid, 13-Ra, 13-cis-β-Retinoic acid, 3,7-Dimethyl-9-(2,6,6-Trimethyl-1-Cyclohexen-1-Yl)-2-Cis-4-Trans-6-Trans-8-Trans-Nonatetraenoic Acid, Absorica, Agn 190013, Amnesteem, Claravis, Isotretinoine, Isotretinoino, Retinoic acid, 13-cis-, Roacutan

Description

Stability Moisture, Temperature, Light Sensitive, Store in freezer
Applications Used as a treatment for severe acne. Presently being studied in conjuction with the treatment of photoaged skin.
References Lerche, C., et al.: Exp. Dermatol., 17, 972 (2008), Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Gan, J., et al.: Chem. Res. Toxicol., 22, 690 (2009), Macejova, D., et al.: Toxicol. Lett., 184, 114 (2009), Chen, P., et al.: Toxicol. App. Pharmacol., 234, 143 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 300.44
• Formula: C₂₀H₂₈O₂
• Color/Form: Neat
• InChI: InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-
• InChI key: InChIKey=SHGAZHPCJJPHSC-XFYACQKRSA-N
• SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C\C(=O)O)C(C)(C)CCC1