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Rhein Methylate 3-(2,3,4,6-Tetraacetate β-D-Glucopyranose)
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Rhein Methylate 3-(2,3,4,6-Tetraacetate β-D-Glucopyranose)

Ref. TR-R318535

5mg
282.00 €
10mg
509.00 €
25mg
1,164.00 €
Estimated delivery in United States, on Monday 24 Mar 2025

Product Information

Name:
Rhein Methylate 3-(2,3,4,6-Tetraacetate β-D-Glucopyranose)
Controlled Product
Synonyms:
  • (2R,3R,4S,5R,6S)-2-(Acetoxymethyl)-6-((8-hydroxy-3-(methoxycarbonyl)-9,10-dioxo-9,10-dihydroanthracen-1-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl Triacetate
Description:

Applications Rhein Methylate 3-(2,3,4,6-Tetraacetate β-D-Glucopyranose) is an intermediate in synthesizing Rhein 8-Glucoside (R318520), which has been seen to exhibit cytotoxic and DNA-damaging properties towards tumor and normal human cells. In addition it has been shown to be an inhibitor of PTP1B (Human Protein Tyrosine Kinase 1B) in vitro. It is an analog of Rhein (318500) which is found in the free state and as glucoside in Rheum spp, Polygonaceae (rhubarb) and in Senna leaves. It is a potential antioxidant resource: endophytic fungi from medicinal plants.
References Wanitschke, Pharmacology, 20, Suppl. 1, 21 (1980); Raimondi, L., et al.: Pharmacol. Res. Commun., 14, 103 (1982); Franchi-Micheli, S., et al.: J. Pharm. Pharmacol., 35, 262 (1983); Li, S. et al.: J. Asian Nat. Prod. Res., 8, 281 (2006); Shi, Y.Q. et al.: Anticancer. Res., 21, 2847 (2001)

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
628.53
Formula:
C30H28O15
Color/Form:
Neat
InChI:
InChI=1S/C30H28O15/c1-12(31)40-11-21-26(41-13(2)32)27(42-14(3)33)28(43-15(4)34)30(45-21)44-20-10-16(29(38)39-5)9-18-23(20)25(37)22-17(24(18)36)7-6-8-19(22)35/h6-10,21,26-28,30,35H,11H2,1-5H3/t21-,26-,27+,28-,30-/m1/s1
InChI key:
InChIKey=SNSPVFCYLPZTRZ-UHFFFAOYSA-N
SMILES:
CCCCCC(=O)C(CCCC)c1oc(=O)c(CCCC)c(O)c1CCCC
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
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