Product Information
Name:Rhodamine-123
Synonyms:
- 3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthylium Chloride
- 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic Acid Methyl Ester Monohydrochloride
- R 22420
- R 302
- RH 123
Brand:TRC
Description:Applications Rhodamine-123 is a fluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Rhodamine 123 (R123), as a typical of P-glycoprotein substrate, was widely used to quantify P-glycoprotein (P-gp) functional efflux activity in vivo. Rhodamine-123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid).References Yumoto, R., et al.: J. Pharmacol. Exp. Ther., 289, 149 (1999), Romiti, N., et al.: Toxicol. Appl. Pharmacol., 183, 83 (2002), Mizuno, N., et al.: Pharmacol. Rev., 559, 425 (2003), del Amo, E., et al.: Eur. J. Pharm. Sci., 36, 200 (2009),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:380.82
Formula:C21H16N2O3·ClH
Color/Form:Neat
InChI:InChI=1S/C21H16N2O3.ClH/c1-25-21(24)15-5-3-2-4-14(15)20-16-8-6-12(22)10-18(16)26-19-11-13(23)7-9-17(19)20;/h2-11,22H,23H2,1H3;1H
SMILES:COC(=O)c1ccccc1-c1c2ccc(N)cc2[o+]c2cc(N)ccc12.[Cl-]
Technical inquiry about: Rhodamine-123
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