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Product Information
Name:
Roxadustat Methyl Ester
Controlled Product
Synonyms:
- methyl 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetate
CAS:
Description:
Applications Roxadustat Methyl Ester is used in the preparation of Roxadustat.Roxadustat (H948180) is a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used to increase white blood cell levels in blood and hematopoietic progenitor cells in bone marrow.It is used for treatment of anemia in patient with chronic kidney disease.
References Wang, Z.: Faming Zhuanli Shenqing. 7 pp. (2018)Provenzano, R., et al.: J. Clin. Pharmacol. 60, 1432 (2020)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
366.367
Formula:
C20H18N2O5
Color/Form:
Neat
InChI:
InChI=1S/C20H18N2O5/c1-12-16-10-14(27-13-6-4-3-5-7-13)8-9-15(16)19(24)18(22-12)20(25)21-11-17(23)26-2/h3-10,24H,11H2,1-2H3,(H,21,25)
InChI key:
InChIKey=QSGJZCCNTOCDRI-UHFFFAOYSA-N
SMILES:
COC(=O)CNC(=O)c1nc(C)c2cc(Oc3ccccc3)ccc2c1O
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-R410460 Roxadustat Methyl Ester
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