Rhynchophylline

CAS: 76-66-4

Ref. TR-R414180

Product Information

• Name: Rhynchophylline
• Synonyms: Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethyl-1,2,2',3',6',7',8',8'a-octahydro-a-(methoxymethylene)-2-oxo-, methyl ester, (aE,1'R,6'R,7'S,8'aS)-, Corynoxan-16-carboxylic acid, 16,17-didehydro-17-methoxy-2-oxo-, methyl ester, (7ß,16E,20a)-, Rhyncophylline (6CI,7CI,8CI), Mitrinermin, Mitrinermine, NSC 21731, Rhynchophyllin, Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethyl-1,2,2',3',6',7',8',8'a-octahydro-a-(methoxymethylene)-2-oxo-, methyl ester, [1'R-[1'a,6'ß,7'a(E),8'aß]]-, Corynoxan-16-carboxylic acid, 16,17-didehydro-17-methoxy-2-oxo-, methyl ester, (7β,16E,20α)-, Rhyncholphylline, Rhyncophylline, Spiro[3H-indole-3,1′(5′H)-indolizine]-7′-acetic acid, 6′-ethyl-1,2,2′,3′,6′,7′,8′,8′a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,1′R,6′R,7′S,8′aS)-, Spiro[3H-indole-3,1′(5′H)-indolizine]-7′-acetic acid, 6′-ethyl-1,2,2′,3′,6′,7′,8′,8′a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, [1′R-[1′α,6′β,7′α(E),8′aβ]]-, methyl (16Z)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate, methyl (3xi,16E,20alpha)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate, methyl (3xi,16Z,20alpha)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate, methyl (7beta,16E,20alpha)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate

Description

Applications Rhynchophylline is a novel erythropoietin-producing hepatocellular A4 (EphA4) inhibitor.
References Fu, A K.Y., et. al.: P. Natl. Acad. Sci. USA., 111, 9959 (2014)

• Brand: TRC

Chemical properties

• Molecular weight: 384.47
• Formula: C₂₂H₂₈N₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C22H28N2O4/c1-4-14-12-24-10-9-22(17-7-5-6-8-18(17)23-21(22)26)19(24)11-15(14)16(13-27-2)20(25)28-3/h5-8,13-15,19H,4,9-12H2,1-3H3,(H,23,26)/b16-13+/t14-,15-,19-,22+/m0/s1
• InChI key: InChIKey=WUANIQLTJBQGJW-HMOJODCTSA-N
• SMILES: CCS[C@@H]1OC(COC(C)=O)[C@H](O[C@@H]2OC(COC(C)=O)[C@H](OC(C)=O)C(OC(C)=O)C2OC(C)=O)C(OC(C)=O)C1OC(C)=O