Riociguat-13C-d3

CAS: 625115-55-1

Ref. TR-R520004

Product Information

• Name: Riociguat-13C-d3
• Synonyms: N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methylcarbamic Acid Methyl Ester-13C-d3, [4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]methylcarbamic Acid Methyl Ester-13C-d3, BAY 63-2521-13C-d3, BAY 632521-13C-d3, Methyl [4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]methylcarbamate-13C-d3
• Brand: TRC
• Description: Applications Riociguat-13C-d3 is the labelled analogue of Riociguat (R520000), which is used in the treatment for pulmonary hypertension.References Frey, R. et al.: J. Clin. Pharmacol., 51, 1051 (2011)

Chemical properties

• Molecular weight: 426.43
• Formula: C₁₉₁₃CH₁₆D₃FN₈O₂
• Color/Form: Neat
• InChI: InChI=1S/C20H19FN8O2/c1-28(20(30)31-2)15-16(22)25-18(26-17(15)23)14-12-7-5-9-24-19(12)29(27-14)10-11-6-3-4-8-13(11)21/h3-9H,10H2,1-2H3,(H4,22,23,25,26)/i1+1D3
• InChI key: InChIKey=WXXSNCNJFUAIDG-KQORAOOSSA-N
• SMILES: [2H][13C]([2H])([2H])N(C(=O)OC)c1c(N)nc(-c2nn(Cc3ccccc3F)c3ncccc23)nc1N