Risperidone 9-Ethylidenecarboxylate Hydrochloride

Ref. TR-R525045

Product Information

• Name: Risperidone 9-Ethylidenecarboxylate Hydrochloride
• Synonyms: 2-(3-(2-(4-(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-7,8-dihydro-4H-pyrido[1,2-a]pyrimidin-9(6H)-ylidene)acetic Acid Hydrochloride

Description

Applications Risperidone 9-Ethylidenecarboxylate Hydrochloride, is the derivative of Risperidone (R525000), which is combined serotonin (5-HT2) and dopamine (D2) receptor antagonist, used for the treatment of schizophrenia, bipolar disorder and behavior problems in people with autism.
References Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),

• Brand: TRC

Chemical properties

• Molecular weight: 466.503646
• Formula: C₂₅H₂₇FN₄O₄
• Color/Form: Neat
• InChI: InChI=1S/C25H27FN4O4.ClH/c1-15-19(25(33)30-9-2-3-17(13-22(31)32)24(30)27-15)8-12-29-10-6-16(7-11-29)23-20-5-4-18(26)14-21(20)34-28-23;/h4-5,13-14,16H,2-3,6-12H2,1H3,(H,31,32);1H/b17-13+
• InChI key: InChIKey=GWNMSSWGOGWIHU-IWSIBTJSSA-N
• SMILES: Cc1nc2n(c(=O)c1CCN1CCC(c3noc4cc(F)ccc34)CC1)CCC/C2=C\C(=O)O.Cl