Rivaroxaban N-Hydrolyse N-5-Chlorothiophene-2-carbaldehyde

CAS: 1151893-81-0

Ref. TR-R538025

Product Information

• Name: Rivaroxaban N-Hydrolyse N-5-Chlorothiophene-2-carbaldehyde
• Synonyms: 2-[2-[[(5-Chloro-2-thienyl)carbonyl][4-[(5S)-5-[[[(5-chloro-2-thienyl)carbonyl]amino]methyl]-2-oxo-3-oxazolidinyl]phenyl]amino]ethoxy]acetic Acid, Rivaroxaban Amine Impurity

Description

Stability Hygroscopic
Applications Rivaroxaban N-Hydrolyse N-5-Chlorothiophene-2-carbaldehyde is an intermediate in synthesizing Rivaroxaban Pseudodimer (R538015), which is an impurity of Rivaroxaban (R538000), a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ansell, J., et al.: Drugs, 64, 1 (2004); Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005); Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005)

• Brand: TRC

Chemical properties

• Molecular weight: 598.48
• Formula: C₂₄H₂₁Cl₂N₃O₇S₂
• Color/Form: Neat
• InChI: InChI=1S/C24H21Cl2N3O7S2/c25-19-7-5-17(37-19)22(32)27-11-16-12-29(24(34)36-16)15-3-1-14(2-4-15)28(9-10-35-13-21(30)31)23(33)18-6-8-20(26)38-18/h1-8,16H,9-13H2,(H,27,32)(H,30,31)/t16-/m0/s1
• InChI key: InChIKey=XEOFNNZMYBBFPT-INIZCTEOSA-N
• SMILES: O=C(O)COCCN(C(=O)c1ccc(Cl)s1)c1ccc(N2C[C@H](CNC(=O)c3ccc(Cl)s3)OC2=O)cc1