Product Information
Name:Ro 67-4853
Controlled Product
Synonyms:
- (9H-Xanthen-9-ylcarbonyl)carbamic Acid Butyl Ester
Brand:TRC
Description:Applications Ro 67-4853 is a positive allosteric modulator of metabotropic glutamate 1 receptor (1,2). Ro 67-4853 exhibits activity at all group I receptors such as human and rat mGlu1/mGlu5. It also enhance glutamate-induced calcium signaling through both the human and mouse mGlu1a receptors.References Knoflach, et al.: Proc. Natl. Acad. Sci. 98, 13402 (2001) Hempstapat, et al.: Mol. Pharmacol., 70, 616 (2006)
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Chemical properties
Molecular weight:325.36
Formula:C19H19NO4
Color/Form:Neat
InChI:InChI=1S/C19H19NO4/c1-2-3-12-23-19(22)20-18(21)17-13-8-4-6-10-15(13)24-16-11-7-5-9-14(16)17/h4-11,17H,2-3,12H2,1H3,(H,20,21,22)
InChI key:InChIKey=PBSUUNCQTRDFCM-UHFFFAOYSA-N
SMILES:COc1ncnc(NS(=O)(=O)c2ccc(NC(C)=O)cc2)c1OC
Technical inquiry about: Ro 67-4853
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