Product Information
Name:Roflumilast
Synonyms:
- 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide
- B 9302-107
- BY 217
- BYK 20869
- Daxas
- Roflumilast,Benzamide
- 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-
- ARQ 151
- Daliresp
- Libertek
Brand:TRC
Description:Applications Roflumilast is a selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; used in treatment of chronic obstructive pulmonary disease.References Hatzelmann, A., et al.: J. Pharmacol. Exp. Ther., 297, 267 (2001); Schmidt, B.M.W., et al.: J. Allergy Clin. Immunol., 108, 530 (2001); Timmer, W., et al.: J. Clin. Pharmacol., 42, 297 (2002); Rabe, K.F., et al.: Lancet, 366, 563 (2005);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:403.21
Formula:C17H14Cl2F2N2O3
Color/Form:Neat
InChI:InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13(26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7,9,17H,1-2,8H2,(H,22,23,24)
InChI key:InChIKey=MNDBXUUTURYVHR-UHFFFAOYSA-N
SMILES:O=C(Nc1c(Cl)cncc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1
Technical inquiry about: Roflumilast
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