Estimated delivery in United States, on Tuesday 12 Nov 2024
Product Information
Name:
Rolapitant Hydrochloride
Controlled Product
Synonyms:
- 1,7-Diazaspiro[4.5]decan-2-one
- 8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-
- hydrochloride (1:1)
- (5S,8S)-
- 1,7-Diazaspiro[4.5]decan-2-one
- 8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-
- monohydrochloride
- (5S,8S)- (9CI)
- Sch 619734
Description:
Applications Rolapitant is an NK1 receptor antagonist that is used in the treatment of chemotherapy-induced nausea and vomiting.
References Rojas, C. et al.: Cancer Treat. Rev., 41, 904 (2015); Navari, R. et al.: Exp. Rev. Anticanc. Ther., 15, 1127 (2015);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
536.94
Formula:
C25H26F6N2O2·ClH
Color/Form:
Neat
InChI:
InChI=1S/C25H26F6N2O2.ClH/c1-16(17-11-19(24(26,27)28)13-20(12-17)25(29,30)31)35-15-23(18-5-3-2-4-6-18)10-9-22(14-32-23)8-7-21(34)33-22;/h2-6,11-13,16,32H,7-10,14-15H2,1H3,(H,33,34);1H/t16-,22-,23-;/m1./s1
InChI key:
InChIKey=VEWAWEMXVUFANV-PVBCUUEWSA-N
SMILES:
C[C@@H](OC[C@@]1(c2ccccc2)CC[C@]2(CCC(=O)N2)CN1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.Cl
MDL:
Melting point:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-R639800 Rolapitant Hydrochloride
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