Product Information
Name:R-(-)-Rolipram
Controlled Product
Synonyms:
- (R)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
- (4R)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
- (-)-Rolipram
Brand:TRC
Description:
Applications R-(-)-Rolipram is a phosphodiesterase IV (PDE4) inhibitor and anti-inflammatory agent with some antidepressant activity. It is the R isomer of (±)-Rolipram (R640040). Potent PDE4 inhibitor.
References Semmler, J., et al.: Int. J. Immunopharmacol.: 15, 409 (1993); Sommer, N., et al.: Nat. Med.: 1, 244 (1995); Robichaud, A., et al.: J. Clin. Invest., 110, 1045 (2002); Card, G., et al.: Structure: 12, 2233 (2004);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:275.343
Formula:C16H21NO3
Color/Form:Neat
InChI:InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)/t12-/m0/s1
InChI key:InChIKey=HJORMJIFDVBMOB-LBPRGKRZSA-N
SMILES:COc1ccc([C@@H]2CNC(=O)C2)cc1OC1CCCC1
Technical inquiry about: R-(-)-Rolipram
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