RTI-55 Hydrochloride

CAS: 141899-24-3

Ref. TR-R701010

Product Information

• Name: RTI-55 Hydrochloride
• Synonyms: 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(4-iodophenyl)-8-methyl-, methyl ester, hydrochloride, [1R-(exo,exo)]- (9CI), 2ß-Carbomethoxy-3ß-(4-iodophenyl)tropane hydrochloride

Description

Stability Very Hygroscopic
Applications RTI-55 is a semi-synthetic alkaloid that is a cocaine analogue belonging to the phenyltropane group. RTI-55 acts as a dopamine reuptake inhibitor (DRI) with siginificant abuse potential. RTI-55 is used to assess the rate of dopamine neuron degradation in the brains of patients with Parkinson’s disease.
References Fujita, M. et al.: J. Chem. Neuroanat., 7, 13 (1994); Elmer, G.I. et al.: Pharmacol. Biochem. Behav., 53, 911 (1996); Coulter, C.L. et al.: Brain Res., 690, 217 (1995);

• Brand: TRC

Chemical properties

• Molecular weight: 421.70
• Formula: C₁₆H₂₀INO₂·ClH
• Color/Form: Neat
• InChI: InChI=1S/C16H20INO2.ClH/c1-18-12-7-8-14(18)15(16(19)20-2)13(9-12)10-3-5-11(17)6-4-10;/h3-6,12-15H,7-9H2,1-2H3;1H/t12-,13+,14+,15-;/m0./s1
• InChI key: InChIKey=FGRGHXZCDYBEJE-PEVLCXCCSA-N
• SMILES: COC(=O)[C@H]1[C@@H](c2ccc(I)cc2)C[C@@H]2CC[C@H]1N2C.Cl