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Product Information
Name:
Ruxolitinib Phosphate
Synonyms:
- 1H-Pyrazole-1-propanenitrile
- β-cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-
- (βR)-
- phosphate (1:1)
- INC 424 phosphate
- INCB 018424 phosphate
- Jakafi
- (Betar)-Beta-Cyclopentyl-4-(7H-Pyrrolo(2,3-D)Pyrimidin-4-Yl)-1H-Pyrazole-1-Propanenitrile
- 1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, (βR)-, phosphate (1:1)
- Incb-018424
- See more synonyms
- Jakavi
- R-Incb018424
- R-Ruxolitinib
- Ruxolitinib (INCB 018424)
- Ruxolitinib phosphate
- Ruxolitinib phosphate salt
CAS:
Description:
Applications The phosphate salt of Ruxolitinib (R702000). Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.
References Shilling, A.D. et al.: Drug Metab. Disp., 38, 2023 (2010); Mesa, R.A.: IDrugs, 13, 394 (2010); Campas-Moya, C.: Drugs Fut., 35, 457 (2010);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
404.36
Formula:
C17H18N6•HPO4
Color/Form:
Off White Solid
InChI:
InChI=1S/C17H18N6.H3O4P/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16;1-5(2,3)4/h6,8-12,15H,1-5H2,(H,19,20,21);(H3,1,2,3,4)/t15-;/m1./s1
SMILES:
N#CC[C@H](C1CCCC1)n1cc(-c2nc[nH]c3nccc2-3)cn1.O=P(O)(O)O
MDL:
Melting point:
Boiling point:
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Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-R702005 Ruxolitinib Phosphate
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