Estimated delivery in United States, on Wednesday 11 Dec 2024
Product Information
Name:
Sacubitril-d4
Controlled Product
Synonyms:
- [1,1'-Biphenyl]-4-pentanoic acid
- ?-[(3-carboxy-1-oxopropyl-2,2,3,3-d4)amino]-a-methyl-
- a-ethyl ester
- (aR,?S)-
- (2R,4S)-4-[(3-Carboxy-1-oxopropyl-2,2,3,3-d4)amino]-4-[(p-phenylphenyl)methyl]-2-methylbutanoic acid ethyl ester
- (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl-2,2,3,3-d4)amino]-2-methylpentanoic acid ethyl ester
- AHU 377-d4
- Sacubitril-D4 (succinate-D4)
- Sucabitril-d4
Description:
Applications Isotope labelled Sacubitril is an antihypertensive drug used in combination with Valsartan (V095750). The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.
References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
415.52
Formula:
C24H4H25NO5
Color/Form:
Light Yellow
InChI:
InChI=1S/C24H29NO5/c1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19/h4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28)/t17-,21+/m1/s1/i13D2,14D2
InChI key:
InChIKey=PYNXFZCZUAOOQC-JKBMVCCKSA-N
SMILES:
[2H]C([2H])(C(=O)O)C([2H])([2H])C(=O)NC(Cc1ccc(-c2ccccc2)cc1)C[C@@H](C)C(=O)OCC
MDL:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-S080897 Sacubitril-d4
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