Product Information
Name:Sacubitril Calcium
Synonyms:
- [S-(R*,S*)]-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-,[1,1'-biphenyl]-4-pentanoic Acid Ethyl Ester Calcium salt
- (2R,4S)-4-[(3-Carboxy-1-oxopropyl)amino]-4-[(p-phenylphenyl)methyl]-2-methylbutanoic acid ethyl ester Calcium salt
- (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic acid ethyl ester Calcium salt
- AHU 377 Calcium salt
Brand:TRC
Description:Applications Sacubitril is an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.References McMurray, J., et al.: N. Eng. J. Med., 371 (2014)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:430.52
Formula:C24H28NOCa2
Color/Form:Neat
InChI:InChI=1S/2C24H29NO5.Ca/c2*1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19;/h2*4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28);/q;;+2/p-2/t2*17-,21+;/m11./s1
InChI key:InChIKey=PYNXFZCZUAOOQC-OQHSHRKDSA-M
SMILES:CCOC(=O)[C@H](C)CC(Cc1ccc(-c2ccccc2)cc1)NC(=O)CCC(=O)[O-]
Technical inquiry about: Sacubitril Calcium
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