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Sacubitril-13C4 Sodium

CAS:

Ref. TR-S080952

10mg
1,530.00€
Sacubitril-13C4 Sodium
TRC

    Product Information

    Name:Sacubitril-13C4 Sodium
    Controlled Product
    Synonyms:
    • (αR,γS)-α-Ethyl γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-Biphenyl]-4-pentanoic Acid-13C4 Sodium Salt (1:1)
    Brand:TRC
    Description:Applications Sacubitril-13C4 Sodium is a derivative Isotope labelled Sacubitril (S080895), which is an antihypertensive drug used in combination with Valsartan (V095750). The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);
    Notice:Our products are intended for lab use only. For any other use, please contact us.

    Chemical properties

    Molecular weight:437.443
    Formula:C4C20H28NNaO5
    Color/Form:Neat
    InChI:InChI=1S/C24H29NO5.Na/c1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19;/h4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28);/q;+1/p-1/t17-,21+;/m1./s1/i13+1,14+1,22+1,23+1;
    InChI key:InChIKey=RRTBVEJIZWGATF-XIKWNFOHSA-M
    SMILES:CCOC(=O)[C@H](C)C[C@@H](Cc1ccc(-c2ccccc2)cc1)N[13C](=O)[13CH2][13CH2][13C](=O)O[Na]

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