Product Information
Name:Savolitinib
Controlled Product
Synonyms:
- Volitinib
- 1-[(1S)-1-Imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-1H-1,2,3-triazolo[4,5-b]pyrazine
- AZD 6094
- HM 5016504
- HMPL 504
Brand:TRC
Description:
Applications Savolitinib is a potent and highly selective c-Met inhibitor. Savoltinib demonstrated anti-tumor efficacy in a panel of cMet-dysregulated gastric cancer PDX models. Savolitinib also demonstrated good antitmuor activities.
References Gavine, P., et al.: Mol. Oncol., 9, 323 (2015); Jia, H., et al.: J. Med. Chem., 57, 7577 (2014);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:345.36
Formula:C17H15N9
Color/Form:Neat
InChI:InChI=1S/C17H15N9/c1-11(12-3-4-15-18-5-6-25(15)10-12)26-17-16(22-23-26)19-8-14(21-17)13-7-20-24(2)9-13/h3-11H,1-2H3/t11-/m0/s1
InChI key:InChIKey=HTPXFGUCAUTOEL-UHFFFAOYSA-N
SMILES:O=C(O)c1cccc2c1Cc1ccccc1-2
Technical inquiry about: Savolitinib
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