Product Information
Name:(2’R,2S,cis)-Saxagliptin
Controlled Product
Synonyms:
- (2'R,2S,cis)-Saxagliptin
- 2-Azabicyclo[3.1.0]hexane-3-carbonitrile
- 2-[(2R)-2-amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-
- (1S,3S,5S)-
- (1S,3S,5S)-2-[(2R)-2-Amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile
Brand:TRC
Description:
Applications (2’R,2S,cis)-Saxagliptin is an impurity of Saxagliptin (S143500); a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes.
References Dong, J., et al.: Bioorg. Med. Chem., 22, 1383 (2014); Feng, J., et al.: J. Med. Chem., 50, 2297 (2007); Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008); Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:315.41
Formula:C18H25N3O2
Color/Form:Neat
InChI:InChI=1S/C18H25N3O2/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17/h10-15,23H,1-7,9,20H2/t10?,11?,12-,13+,14+,15+,17?,18?/m1/s1
SMILES:N#C[C@@H]1C[C@@H]2C[C@@H]2N1C(=O)[C@H](N)[C@@]12C[C@@H]3C[C@@H](C[C@@](O)(C3)C1)C2
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