Estimated delivery in United States, on Tuesday 18 Feb 2025
Product Information
Name:
(2’R,2R,trans)-Saxagliptin
Controlled Product
Synonyms:
- (2'R,2R,trans)-Saxagliptin
- 2-Azabicyclo[3.1.0]hexane-3-carbonitrile
- 2-[(2R)-2-amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-
- (1S,3R,5S)- (ACI)
- (1S,3R,5S)-2-[(2R)-2-Amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile (ACI)
- (1S
Description:
Applications (2’R,2R,trans)-Saxagliptin is an impurity of Saxagliptin (S143500); a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes.
References Dong, J., et al.: Bioorg. Med. Chem., 22, 1383 (2014); Feng, J., et al.: J. Med. Chem., 50, 2297 (2007); Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008); Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
315.41
Formula:
C18H25N3O2
Color/Form:
Neat
InChI:
InChI=1S/C18H25N3O2/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17/h10-15,23H,1-7,9,20H2/t10?,11?,12-,13-,14+,15+,17?,18?/m1/s1
SMILES:
N#C[C@H]1C[C@@H]2C[C@@H]2N1C(=O)[C@H](N)[C@@]12C[C@@H]3C[C@@H](C[C@@](O)(C3)C1)C2
MDL:
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Density:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-S143480 (2’R,2R,trans)-Saxagliptin
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