Product Information
Name:SB 431542
Controlled Product
Synonyms:
- 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide
Brand:TRC
Description:
Applications SB 431542 is a known Src family kinase inhibitor that effectively blocks the transforming growth factor-β1-induced cell migration and invasion in both established and primary carcinoma cells. Potent TGF-beta inhibitor.
References Tobias, B., et al.: Cancer. Chemother. Pharmacol., 70, 221 (2012); James, J., et al.: Molec. Cancer. Therap., 11, 930 (2012);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:384.39
Formula:C22H16N4O3
Color/Form:Neat
InChI:InChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)
InChI key:InChIKey=FHYUGAJXYORMHI-UHFFFAOYSA-N
SMILES:NC(=O)c1ccc(-c2nc(-c3ccc4c(c3)OCO4)c(-c3ccccn3)[nH]2)cc1
Technical inquiry about: SB 431542
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