Product Information
Name:Sch 58053
Controlled Product
Synonyms:
- (1R)-7-(4-chlorophenyl)-2-(4-fluorophenyl)-7-hydroxy-1-(4-hydroxyphenyl)-2-azaspiro[3.5]nonan-3-one
Brand:TRC
Description:Applications An analog of Ezetimibe (E975000). SCH 58053 is a potent, rapid, and selective inhibitor of lymphatic cholesterol transport in the intestine.References Ly, H., et al.: Biochem. J., 286, 937 (1992), Dujovne, C., et al.: Am. J. Cardiol., 90, 1092 (2002), Repa, J., et al.: J. Lipid Res., 43, 1864 (2002), Knopp, R., et al.: Eur. Heart J., 24, 729 (2003), Altmann, S., et al.: Science, 303, 1201 (2004),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:451.92
Formula:C26H23ClFNO3
Color/Form:Neat
InChI:InChI=1S/C26H23ClFNO3/c27-19-5-3-18(4-6-19)26(32)15-13-25(14-16-26)23(17-1-11-22(30)12-2-17)29(24(25)31)21-9-7-20(28)8-10-21/h1-12,23,30,32H,13-16H2/t23-,25?,26?/m1/s1
InChI key:InChIKey=DPZUDTYEZMUJDW-GMUMFXLYSA-N
SMILES:O=C1N(c2ccc(F)cc2)[C@H](c2ccc(O)cc2)C12CCC(O)(c1ccc(Cl)cc1)CC2
Technical inquiry about: Sch 58053
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