Product Information
Name:Sch 58053-d4
Controlled Product
Synonyms:
- (3R,4β,7α)-7-(4-Chlorophenyl-d4)-2-(4-fluorophenyl)-7-hydroxy-3-(4-hydroxyphenyl)-2-azaspiro[3.5]nonan-1-one
Brand:TRC
Description:Applications A labelled analog of Ezetimibe (E975000). SCH 58053 is a potent, rapid, and selective inhibitor of lymphatic cholesterol transport in the intestine.References Ly, H., et al.: Biochem. J., 286, 937 (1992), Dujovne, C., et al.: Am. J. Cardiol., 90, 1092 (2002), Repa, J., et al.: J. Lipid Res., 43, 1864 (2002), Knopp, R., et al.: Eur. Heart J., 24, 729 (2003), Altmann, S., et al.: Science, 303, 1201 (2004),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:455.95
Formula:C26H19D4ClFNO3
Color/Form:Neat
InChI:InChI=1S/C33H29ClFNO3/c34-26-10-8-25(9-11-26)33(38)20-18-32(19-21-33)30(36(31(32)37)28-14-12-27(35)13-15-28)24-6-16-29(17-7-24)39-22-23-4-2-1-3-5-23/h1-17,30,38H,18-22H2/t30-,32?,33?/m1/s1/i8D,9D,10D,11D
InChI key:InChIKey=DPZUDTYEZMUJDW-HLGBRDQESA-N
SMILES:[2H]c1c(Cl)c([2H])c([2H])c([C@]2(O)CC[C@]3(CC2)C(=O)N(c2ccc(F)cc2)[C@@H]3c2ccc(O)cc2)c1[2H]
Technical inquiry about: Sch 58053-d4
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