Scopolamine N-Oxide

CAS: 97-75-6

Ref. TR-S200020

Product Information

• Name: Scopolamine N-Oxide
• Synonyms: (αS)-α-(Hydroxymethyl)benzeneacetic Acid (1α,2β,4β,5α,7β)-9-Methyl-9-oxido-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl Ester, 6β,7β-Epoxy-1αH,5αH-tropan-3α-ol (-)-Tropate 8-Oxide, [7(S)-(1α,2β,4β,5α,7β)]-α-(Hydroxymethyl)benzeneacetic Acid 9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl Ester N-Oxide, Scopolamine, N-Oxide, 3-Oxa-9-azatricyclo[3.3.1.02,4]nonane Benzeneacetic Acid Deriv., Genoscopolamine, Hyoscinamine Oxide, Hyoscine N-Oxide, Hyoscineamine Oxide, Oxicopolamina, Scolamine, Scolen, Scopodex, Scopolamine aminoxide, Seamalin
• Brand: TRC
• Description: Stability HygroscopicApplications Scopolamine N-Oxide is an impurity of Scopolamine (S200000), an acetylcholine antagonist used in the treatment of motion sickness and also used as antiemetic, antispasmodic, mydriatic, preanesthetic agents.References Shahwar, D., et al.: Turk. J. Chem., 36, 257 (2012); Paula, S., et al.: J. Med. Chem., 47, 133 (2004); Wu, H.L., et al.: J. Chromatograph. A., 802, 107 (1998); Phillipson, J.D., et al.: J. Pharma. Pharmcol., 25, 116 (1973)

Chemical properties

• Molecular weight: 319.35
• Formula: C₁₇H₂₁NO₅
• Color/Form: Neat
• InChI: InChI=1S/C17H21NO5/c1-18(21)13-7-11(8-14(18)16-15(13)23-16)22-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3/t11-,12-,13-,14+,15-,16+,18+/m1/s1
• InChI key: InChIKey=GSYQNAMOFFWAPF-PPOBMCMBSA-N
• SMILES: C[N+]1([O-])[C@H]2C[C@H](OC(=O)[C@H](CO)c3ccccc3)C[C@@H]1[C@H]1O[C@@H]21