Selepam

CAS: 36735-22-5

Ref. TR-S253000

Product Information

• Name: Selepam
• Synonyms: 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepine-2-thione, 7-Chloro-1-(2,2,2-trifluoroethyl)-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepine-2-thione, 7-Chloro-1-(2,2,2-trifluoroethyl)-1,3-dihydro-5-(o-fluorophenyl)-2H-1,4-benzodiazepine-2-thione, 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepine-2-thione, Chazepam, Doral, Dormalin, Nsc 309702, Oniria, Prosedar, Quazepam, Quazium, Sch 16134

Description

Applications Selepam is a benzodiazepine derivative drug and is known to bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation, anticonvulsant activty, motor coordination and memory. Selepam is known to induce motor impairment and exerts hypnotic properties. Selepam is often used for the treatment of insomina.
References Rasmussen, H.B., et al.: Pharma. Genom., 22, 471 (2012); Noorizadeh, H., et al.: Medn. Chem. Rsch., 21, 4357 (2012); Mauri, M.C., et al.: Int. J. Clin. Pharmacol. Res., 13, 173 (1993);

• Brand: TRC

Chemical properties

• Molecular weight: 386.79
• Formula: C₁₇H₁₁ClF₄N₂S
• Color/Form: Neat
• InChI: InChI=1S/C17H11ClF4N2S/c18-10-5-6-14-12(7-10)16(11-3-1-2-4-13(11)19)23-8-15(25)24(14)9-17(20,21)22/h1-7H,8-9H2
• InChI key: InChIKey=IKMPWMZBZSAONZ-UHFFFAOYSA-N
• SMILES: Fc1ccccc1C1=NCC(=S)N(CC(F)(F)F)c2ccc(Cl)cc21