CAS 36735-22-5

Quazepam

Description:

Quazepam is a medication primarily classified as a benzodiazepine, which is used for the treatment of insomnia. It acts as a central nervous system depressant, promoting sedation and facilitating sleep. The chemical structure of quazepam includes a benzodiazepine core, which is characterized by a fused benzene and diazepine ring. Its mechanism of action involves enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to increased inhibitory neurotransmission. Quazepam is known for its relatively long half-life, which can result in residual effects the following day, making it important for patients to be cautious about activities requiring full alertness. Common side effects may include drowsiness, dizziness, and potential dependence with prolonged use. Due to its sedative properties, quazepam is typically prescribed for short-term use, and its use should be monitored by healthcare professionals to mitigate risks associated with tolerance and withdrawal. As with all medications, it is essential to follow prescribed dosages and consult a healthcare provider for any concerns.

Formula: C₁₇H₁₁ClF₄N₂S

InChI: InChI=1S/C17H11ClF4N2S/c18-10-5-6-14-12(7-10)16(11-3-1-2-4-13(11)19)23-8-15(25)24(14)9-17(20,21)22/h1-7H,8-9H2

InChI key: InChIKey=IKMPWMZBZSAONZ-UHFFFAOYSA-N

SMILES: C(C(F)(F)F)N1C=2C(C(=NCC1=S)C3=C(F)C=CC=C3)=CC(Cl)=CC2

Synonyms:

• 7-Chloro-1-(2,2,2-trifluoroethyl)-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepine-2-thione
• 7-Chloro-1-(2,2,2-trifluoroethyl)-1,3-dihydro-5-(o-fluorophenyl)-2H-1,4-benzodiazepine-2-thione
• 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepine-2-thione
• Chazepam
• Doral
• Dormalin
• Nsc 309702
• Oniria
• Prosedar
• Quazepam
• Quazium
• Sch 16134
• Selepam

Selepam

Controlled Product

CAS: 36735-22-5

Applications Selepam is a benzodiazepine derivative drug and is known to bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation, anticonvulsant activty, motor coordination and memory. Selepam is known to induce motor impairment and exerts hypnotic properties. Selepam is often used for the treatment of insomina.
References Rasmussen, H.B., et al.: Pharma. Genom., 22, 471 (2012); Noorizadeh, H., et al.: Medn. Chem. Rsch., 21, 4357 (2012); Mauri, M.C., et al.: Int. J. Clin. Pharmacol. Res., 13, 173 (1993);

Formula: C₁₇H₁₁ClF₄N₂S

Color and Shape: Neat

Molecular weight: 386.79

Ref: TR-S253000

Selepam-d4

Controlled Product

CAS: 36735-22-5

Formula: C₁₇D₄H₇ClF₄N₂S

Color and Shape: Neat

Molecular weight: 390.819

Ref: TR-S253002

Selepam (100 μg/mL in Acetonitrile)

Controlled Product

CAS: 36735-22-5

Formula: C₁₇H₁₁ClF₄N₂S

Color and Shape: Single Solution

Molecular weight: 386.79

Ref: TR-KIT7213

Selepam (1 mg/ml in Acetonitrile)

Controlled Product

CAS: 36735-22-5

Formula: C₁₇H₁₁ClF₄N₂S

Color and Shape: Single Solution

Molecular weight: 386.79

Ref: TR-KIT7210

Quazepam

Controlled Product

CAS: 36735-22-5

Anticonvulsants, hypnotics and sedatives

Formula: C₁₇H₁₁ClF₄N₂S

Color and Shape: White Off-White Light Yellow Powder

Molecular weight: 386.02676

Ref: 45-1592205