Semustine

CAS: 13909-09-6

Ref. TR-S258205

Product Information

• Name: Semustine
• Synonyms: Urea, N-(2-chloroethyl)-N'-(4-methylcyclohexyl)-N-nitroso-, Urea, 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso- (8CI), N-(2-Chloroethyl)-N'-(4-methylcyclohexyl)-N-nitrosourea, 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea, 1-(2-Chloroethyl), 1-(2-Chloroethyl)-1-Formyl-3-(4-Methylcyclohexyl)Urea, 1-(2-Chloroethyl)-3-(4-Methylcyclohexyl)-1-Nitrosourea, 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosurea, 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)nitrosourea, Icig 1110, Me-CCNU, Methyl lomustine, Methyl-CCNU, N-(2-Chloroethyl)-N′-(4-methylcyclohexyl)-N-nitrosourea, N′-(4-Methylcyclohexyl)-N-(2-chloroethyl)-N-nitrosourea, Urea, 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-, Urea, N-(2-chloroethyl)-N′-(4-methylcyclohexyl)-N-nitroso-

Description

Applications Semustine is an alkylating agent and interstrand DNA cross linker. Anti-cancer chemotherapeutic agents, which are used in the treatment of different types of cancer such as brain tumors, resistant Hodgkin’s disease, lung cancer and malignant melanoma.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Agarwal, S., et al.: J. Photochem. Photobiol. B, Biol., 166, 1-11 (2017)

• Brand: TRC

Chemical properties

• Molecular weight: 247.722
• Formula: C₁₀H₁₈ClN₃O₂
• Color/Form: Neat
• InChI: InChI=1S/C10H18ClN3O2/c1-8-2-4-9(5-3-8)12-10(15)14(13-16)7-6-11/h8-9H,2-7H2,1H3,(H,12,15)
• InChI key: InChIKey=FVLVBPDQNARYJU-UHFFFAOYSA-N
• SMILES: CC1CCC(NC(=O)N(CCCl)N=O)CC1