TR-S487302 - sinensetin-d3 | 1438399-79-1

Sinensetin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Sinensetin

Sinensetin is a polymethoxylated flavonoids in citrus fruit, as a novel antiangiogenesis agent, has potential for anti-carcinogenesis, antitumor, and cardiovascular protective activity.

<p>Sinensetin, a citrus flavone, has antiangiogenic, anti-inflammatory properties, and promotes fat formation and breakdown.</p>

Oxygen-heterocyclic compound

<p>Applications Sinensetin exhibits anti-fungal, anti-histamine activity; induce cell differentiation, inhibition of linoleic acid oxidation, inhibition of white blood cells in the human zona protein Interleukin -1-induced expression of tissue factor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Elliott, A., et al.: Biochem. Pharmacol., 44, 1603 (1992), Furuta, S., et al.: J. Food Sci., 62, 526 (1997),<br></p>

<p>Sinensetin is a polymethoxyflavone, which is a type of flavonoid compound. It is predominantly sourced from citrus peels, particularly those of oranges. The compound exhibits multiple biological activities, primarily through its mode of action that involves modulating inflammatory pathways and oxidative stress responses. Sinensetin achieves this by inhibiting pro-inflammatory cytokines and enzymes such as cyclooxygenase, thereby reducing inflammation processes at the cellular level.</p>

<p>This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&amp;D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>

<p>Applications Labelled Eupatorin 5-Methyl Ether (E938850). Sinensetin, eupatorin, 3'-hydroxy-5,6,7,4'-tetramethoxyflavone and rosmarinic acid contents and antioxidative effect of Orthosiphon stamineus from Malaysia.<br>References Elliott, A., et al.: Biochem. Pharmacol., 44, 1603 (1992), Furuta, S., et al.: J. Food Sci., 62, 526 (1997),<br></p>

<p>Sinensetin is an anti-inflammatory compound that belongs to the chromones class of compounds. Sinensetin has been shown to have anti-inflammatory properties at high temperatures in experimental models. The mechanism of action for sinensetin is not well understood, but it may be due to the inhibition of prostaglandin synthesis or by direct interaction with TNF-α. Sinensetin also has antioxidant and antifungal properties, which are attributed to its ability to scavenge free radicals and inhibit lipid peroxidation. Sinensetin was found in a variety of plants from China, including Acanthopanax senticosus and Eurycoma longifolia.</p>

5-Desmethylsinensetin

Isosinensetin

Isosinensetin shows antioxidant and HIV-1 protease inhibiting activities.