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SMAD3 Inhibtor, SIS 3
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SMAD3 Inhibtor, SIS 3

CAS: 1009104-85-1

Ref. TR-S564500

Estimated delivery in United States, on Thursday 17 Dec 2020

Product Information

Name:
SMAD3 Inhibtor, SIS 3
Synonyms:
  • 1-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-propen-1-one
Description:

Applications SMAD3 Inhibitor, SIS3 selectively inhibits TGF- and activin. It has been shown to reduce TGF-1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts.
References Jinnin, M., et al.: Mol. Pharmacol., 69, 597 (2006)

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Chemical properties

Molecular weight:
453.53
Formula:
C28H27N3O3
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Hazard Info

UN Number:
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