Product Information
Name:SN-38 Carboxylate Disodium Salt
Controlled Product
Synonyms:
- (αS)-α,12-Diethyl-9,11-dihydro-α,2-dihydroxy-8-(hydroxymethyl)-9-oxo-9-indolizino[1,2-b]quinoline-7-acetic Acid Disodium Salt
- SN 38 Acid Sodium Salt
Brand:TRC
Description:Applications The active metabolite of Irinotecan (carboxylate form). SN-38 lactone and carboxylate may be considered pharmacokinetically distinct agents.References Billecke, S., et al.: Drug Metab. Dispos., 28, 1335 (2000), Teiber, J., et al.: Biochem. Pharmacol., 66, 887 (2003), Ashley, G., et al.: J. Antibiot., 57, 224 (2004),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:454.39
Formula:C22H20N2Na2O6
Color/Form:Neat
InChI:InChI=1S/C22H22N2O6.2Na/c1-3-12-13-7-11(26)5-6-17(13)23-19-14(12)9-24-18(19)8-16(15(10-25)20(24)27)22(30,4-2)21(28)29;;/h5-8,25-26,30H,3-4,9-10H2,1-2H3,(H,28,29);;/q;2*+1/p-2/t22-;;/m0../s1
InChI key:InChIKey=OPIACBXCNWXXGI-IKXQUJFKSA-L
SMILES:CCc1c2c(nc3ccc(O[Na])cc13)-c1cc([C@@](O)(CC)C(=O)O[Na])c(CO)c(=O)n1C2
Technical inquiry about: SN-38 Carboxylate Disodium Salt
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