Solifenacin Succinate

CAS: 242478-38-2

Ref. TR-S676701

Product Information

• Name: Solifenacin Succinate
• Synonyms: (3R)-1-Azabicyclo[2.2.2]octan-3-yl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrogen butanedioate, (3R)-1-azabicyclo[2.2.2]oct-3-yl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate butanedioate (1:1), 1-Azabicyclo[2.2.2]octan-8-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate butanedioic acid, 1-azabicyclo[2.2.2]oct-3-yl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate, 1-azabicyclo[2.2.2]oct-3-yl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate butanedioate (1:1), 2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-1-phenyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester, (1S)-, butanedioate (1:1), Butanedioic acid, compd. with (1S)-(3R)-1-azabicyclo[2.2.2]oct-3-yl 3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylate (1:1), Vesicare, Vesikur, Ym 67905, Solifenacin succinate

Description

Stability Hygroscopic
Applications Muscarinic M3 receptor antagoinst. Used in treatment of urinary incontinence.
References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002), Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004), Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004), Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005), Habb, F., et al.: Eur. Urol. 47, 376 (2005), Payne, C.K., et al.: Drugs, 66, 175 (2006),

• Brand: TRC

Chemical properties

• Molecular weight: 480.55
• Formula: C₂₃H₂₆N₂O₂·C₄H₆O₄
• Color/Form: White
• InChI: /m0./s1, 5-3(6)1-2-4(7)8/h1-9,18,21-22H,10-16H2, 1-2H2,(H,5,6)(H,7,8)/t21-,22-, InChI=1S/C23H26N2O2.C4H6O4/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19
• InChI key: InChIKey=RXZMMZZRUPYENV-VROPFNGYSA-N
• SMILES: O=C(O)CCC(=O)O.O=C(O[C@H]1C[N@]2CC[C@@H]1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1