Solifenacin-d7 Hydrochloride

CAS: 180468-39-7

Ref. TR-S676704

Product Information

• Name: Solifenacin-d7 Hydrochloride
• Synonyms: (1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic-d7 Acid, (3R)-1-Azabicyclo-[2.2.2]oct-3-yl Ester-d7 Hydrochloride, (1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3R)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochlorid, (1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3R)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochloride, (3R)-1-azabicyclo[2.2.2]oct-3-yl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrochloride (1:1)

Description

Applications Solifenacin-d7 hydrochloride is deuterium labelled Solifenacin hydrochloride (S676700), which is a Muscarinic M3 receptor antagoinst and used to treat urinary incontinence.
References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002), Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004), Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004), Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005), Habb, F., et al.: Eur. Urol. 47, 376 (2005), Payne, C.K., et al.: Drugs, 66, 175 (2006),

• Brand: TRC

Chemical properties

• Molecular weight: 405.97
• Formula: C₂₃H₂₀D₇ClN₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C23H26N2O2.ClH/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19;/h1-9,18,21-22H,10-16H2;1H/t21-,22-;/m0./s1/i13D2,14D2,16D2,21D
• InChI key: InChIKey=YAUBKMSXTZQZEB-HACHUTOTSA-N
• SMILES: Cl.[2H]C1([2H])C[C@H]2CC([2H])([2H])[N@@]1C([2H])([2H])[C@]2([2H])OC(=O)N1CCc2ccccc2[C@@H]1c1ccccc1