Product Information
- 3-(4-Morpholinylsulfonyl)-Benzoic Acid (2E)-2-[1-(5-chloro-2-hydroxyphenyl)ethylidene]hydrazide
- BHC 110 inhibitor VII
- Histone Lysine Demethylase Inhibitor XIV
- KIAA 1718 inhibitor VII
- LSD 1 inhibitor VII
Applications SP 2509 reduces the effect of the LSD1 binding to CoREST, resulting in increased methylation of H3K4 and driving increased expression of p21, p27 and CCAAT/enhancer binding protein α in acute myeloid leukemia cells. Anti-leukemia agent.
References Sorna, V. et al.: J. Med. Chem., 56, 9496 (2013); Fiskus, W. et al.: Leukemia, 11, 2155 (2014);
Chemical properties
Technical inquiry about: TR-S679000 SP 2509
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