17b-Spiro[5-androsten-17,2'-oxiran]-3b-ol

CAS: 847-75-6

Ref. TR-S682975

Product Information

• Name: 17b-Spiro[5-androsten-17,2'-oxiran]-3b-ol
• Synonyms: (3beta,17beta)-Spiro[androst-5-ene-17,2'-oxiran]-3-ol, BNN 50, BNN20, 17beta,171-Epoxy-17-methyl Androst-5-en-3beta-ol
• Brand: TRC
• Description: Applications 17β-Spiro[5-androsten-17,2'-oxiran]-3β-ol is an intermediate in the synthesis of 7β-Acetylthio-17α-ethoxymethy Testosterone which is an impurity of Spironolactone (S683000), which is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome.References Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975),

Chemical properties

• Molecular weight: 302.45
• Formula: C₂₀H₃₀O₂
• Color/Form: Neat
• InChI: InChI=1S/C20H30O2/c1-18-8-5-14(21)11-13(18)3-4-15-16(18)6-9-19(2)17(15)7-10-20(19)12-22-20/h3,14-17,21H,4-12H2,1-2H3/t14-,15+,16-,17-,18-,19-,20+/m0/s1
• InChI key: InChIKey=CSMRZKBUOFUSRQ-JHCHYBNPSA-N
• SMILES: O=C(/C=C/c1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O)NCCCCCCNC(=O)C(F)(F)F