Product Information
Name:SSR128129E
Controlled Product
Synonyms:
- 2-Amino-5-[(1-methoxy-2-methyl-3-indolizinyl)carbonyl]-benzoic Acid Sodium Salt
- 2-Amino-5-[(1-methoxy-2-methyl-3-indolizinyl)carbonyl]-benzoic Acid Monosodium Salt
- SSR 128129E
- Sodium 2-Amino-5-[(1-methoxy-2-methylindolizin-3-yl)carbonyl]benzoate
Brand:TRC
Description:Applications SSR128129E (SSR) is an potent FGFR inhibitor, which inhibits fibroblast growth factor receptor (FGFR). Oral delivery of SSR128129E inhibits arthritis and tumors that are relatively refractory to anti-vascular endothelial growth factor receptor-2 antibodies.
References Bono, F., et al.: Cancer Cell., 23, 477 (2013); Dol-Gleizes, F., et al.: PLoS One, 8, e80027 (2013)
References Bono, F., et al.: Cancer Cell., 23, 477 (2013); Dol-Gleizes, F., et al.: PLoS One, 8, e80027 (2013)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:346.31
Formula:C18H15N2NaO4
Color/Form:Yellowish Solid
InChI:InChI=1S/C18H16N2O4.Na/c1-10-15(20-8-4-3-5-14(20)17(10)24-2)16(21)11-6-7-13(19)12(9-11)18(22)23;/h3-9H,19H2,1-2H3,(H,22,23);/q;+1/p-1
InChI key:InChIKey=JFBMSTWZURKQOC-UHFFFAOYSA-M
SMILES:COc1c(C)c(C(=O)c2ccc(N)c(C(=O)O[Na])c2)n2ccccc12
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