Stavudine

CAS: 3056-17-5

Ref. TR-S685250

Product Information

• Name: Stavudine
• Synonyms: 1-[(2R,5S)-5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, Zidovudine Imp. A (EP), 3'-Deoxy-2'-thymidinene, 2',3'-Didehydro-3'-deoxythymidine, 3'-Deoxy-2',3'-didehydrothymidine, Avostav, BMY 27857, D 4T (nucleoside), NSC 163661, Sanilvudine, Staduvine, Stag, Stavir, Virostav, Zerit, d4T, 1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine, Ph Eur Zidovudine Impurity A, GR 92955X, Zidovudine Impurity A, 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione, 1-[5-(Hydroxymethyl)-2,5-Dihydrofuran-2-Yl]-5-Methyl-Hexahydropyrimidine-2,4-Dione, 2',3'-Didehydro-3'-Deoxythymidine, 2,4(1H,3H)-Pyrimidinedione, 1-[(2R,5S)-2,5-dihydro-5-(hydroxymethyl)-2-furanyl]-5-methyl-, 2′,3′-Didehydro-2′,3′-dideoxythymidine, 2′,3′-Didehydro-3′-deoxythymidine, 2′-Thymidinene, 3′-deoxy-, 3'-Deoxy-2',3'-Didehydrothymidine, 3'-Deoxythymidin-2'-Ene, 3′-Deoxy-2′,3′-didehydrothymidine, Bmy 27857, Melxicap, Thymidine, 2′,3′-didehydro-3′-deoxy-, Thymine, 1-(2,3-dideoxy-β-<span class="text-smallcaps">D</span>-glycero-pent-2-enofuranosyl)-

Description

Impurity Zidovudine EP Impurity A
Applications Stavudine (Zidovudine EP Impurity A) is used as an antiviral. A reverse transcriptase inhibitor.
References Mansuri, M.M., et al.: Antimicrob. Ag. Chemother., 34, 637 (1990), Cretton, E.M., et al.: Antimicrob. Ag. Chemother., 37, 1816 (1993), Browne, M.J., et al.: J. Infec. Dis., 167, 21 (1993)

• Brand: TRC

Chemical properties

• Molecular weight: 224.21
• Formula: C₁₀H₁₂N₂O₄
• Color/Form: White
• InChI: InChI=1S/C10H12N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h2-4,7-8,13H,5H2,1H3,(H,11,14,15)/t7-,8+/m0/s1
• InChI key: InChIKey=XNKLLVCARDGLGL-JGVFFNPUSA-N
• SMILES: Cc1cn([C@H]2C=C[C@@H](CO)O2)c(=O)[nH]c1=O