Streptozotocin

CAS: 18883-66-4

Ref. TR-S687550

Product Information

• Name: Streptozotocin
• Synonyms: 2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-D-glucose, Glucopyranose, 2-deoxy-2-(3-methyl-3-nitrosoureido)-, D- (8CI), Estreptozocin, NSC 37917, NSC 85998, STRZ, STZ, Streptozocin, Streptozoticin, U 9889, Zanosar, (5xi)-2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-D-lyxo-hexopyranose, 2-Deoxy-2-(((Methylnitrosoamino)Carbonyl)Amino)-D-Glucose, 2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-<span class="text-smallcaps">D</span>-glucose, 2-Desoxy-2-(3-Methyl-3-Nitrosoureido)-D-Glucopyranose, 2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-D-glucopyranose, 2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-alpha-D-glucopyranose, 2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-beta-D-glucopyranose, <span class="text-smallcaps">D</span>-Glucose, 2-deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-, D-Glucose, 2-deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-, Estreptozocina, Glucopyranose, 2-deoxy-2-(3-methyl-3-nitrosoureido), Glucopyranose, 2-deoxy-2-(3-methyl-3-nitrosoureido)-, <span class="text-smallcaps">D</span>-, Glucopyranose, 2-deoxy-2-(3-methyl-3-nitrosoureido)-, D-, Nsc 37917, Nsc 85998, Streptozocine, Strz

Description

Applications Streptozotocin is used in the treatment metastatic cancer of the pancreatic islet cells. Streptozotocin has a highlrisk of toxicity and is generally limited to cancers that are inoperable.
References Meyer, D.J. et al.: Am. J. Vet. Res., 37, 1221 (1976); Kouvaraki, M.A. et al.: J. Clin. Oncol., 22, 4762 (2004); Moore, A.S. et al.: Am. Vet. Med. Assoc., 221, 811 (2002):

• Brand: TRC

Chemical properties

• Molecular weight: 265.22
• Formula: C₈H₁₅N₃O₇
• Color/Form: Neat
• InChI: InChI=1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7?/m1/s1
• InChI key: InChIKey=ZSJLQEPLLKMAKR-UHEPRFFZSA-N
• SMILES: CN(N=O)C(=O)NC1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O