N6-Succinyl Adenosine

CAS: 4542-23-8

Ref. TR-S688825

Product Information

• Name: N6-Succinyl Adenosine
• Synonyms: (2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid, (2S)-2-({9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-9H-purin-6-yl}amino)butanedioic acid (non-preferred name), 4542-23-8, 6-(1,2-Dicarboxyethylamino)-9-β-<span class="text-smallcaps">D</span>-ribofuranosylpurine, <span class="text-smallcaps">L</smallcap>-Aspartic acid, N-(9-β-<smallcap>D</span>-ribofuranosyl-9H-purin-6-yl)-, Adenosine, N-(1,2-dicarboxyethyl)-, (S)-, Aspartic acid, N-(9-β-<span class="text-smallcaps">D</smallcap>-ribofuranosyl-9H-purin-6-yl)-, <smallcap>L</span>-, Aspartic acid, N-9-ribofuranosyl-9H-purin-6-yl-, N-(9-b-D-ribofuranosyl-9H-purin-6-yl)-L-Aspartic acid, N-(9-β-<span class="text-smallcaps">D</smallcap>-Ribofuranosyl-9H-purin-6-yl)-<smallcap>L</span>-aspartic acid, N⁶-Succinyloadenosine, Succinoadenosine

Description

Applications Succinyladenosine (S-Ado) is a biochemical marker of adenylosuccinase deficiency - the genetic defect of purine de novo synthesis. S-Ado has been previously reported as normally undetectable in cerebrospinal fluid (CSF) of children not suffering from this defect.
References Wevers, R., et al.: Clin. Chem., 41, 744 (1995), Nassogne, M., et al.: Brain Dev., 22, 383 (2000), Jurecka, A., et al.: Mol. Genet., 94, 435 (2008),

• Brand: TRC

Chemical properties

• Molecular weight: 383.31
• Formula: C₁₄H₁₇N₅O₈
• Color/Form: White To Light Yellow
• InChI: InChI=1S/C14H17N5O8/c20-2-6-9(23)10(24)13(27-6)19-4-17-8-11(15-3-16-12(8)19)18-5(14(25)26)1-7(21)22/h3-6,9-10,13,20,23-24H,1-2H2,(H,21,22)(H,25,26)(H,15,16,18)/t5-,6+,9+,10+,13-/m0/s1
• InChI key: InChIKey=VKGZCEJTCKHMRL-MDBUBQOGSA-N
• SMILES: O=C(O)C[C@H](Nc1ncnc2c1ncn2[C@H]1O[C@H](CO)[C@@H](O)[C@H]1O)C(=O)O