Sulfamethizole

CAS: 144-82-1

Ref. TR-S689005

Product Information

• Name: Sulfamethizole
• Synonyms: Sulfasalazine Imp. J (EP), 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide, Benzenesulfonamide, 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)-, Sulfanilamide, N1-(5-methyl-1,3,4-thiadiazol-2-yl)- (6CI,7CI,8CI), 2-Methyl-5-sulfanilamido-1,3,4-thiadiazole, 2-Sulfanilamido-5-methyl-1,3,4-thiadiazole, 4-Amino-N-(5-methyl-[1,3,4]thiadiazol-2-yl)benzenesulfonamide, 5-Methyl-2-sulfanilamido-1,3,4-thiadiazole, Ayerlucil, Famet, Lucosil, Methazol, Microsul, N-(5-Methyl-1,3,4-thiadiazol-2-yl)-4-aminobenzenesulfonamide, N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide, Renasul, Rufol, Salimol, Sulfamethiazole, Sulfamethizol, Sulfamethylthiadiazole, Sulfapyelon, Sulfstat, Sulfurine, Sulphamethizole, Tetracid, Thidicur, Thiosulfil, Thiosulfil Forte, Ultrasul, Urocydal, Urodiaton, Urolucosil, Urosulfin, VK 53, Sulfamethizol, N¹-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide, Sulfametizol, Sulfanilamide, N1-(5-methyl-1,3,4-thiadiazol-2-yl)-, Sulfanilamide, N¹-(5-methyl-1,3,4-thiadiazol-2-yl)-, Vk 53

Description

Applications Sulfamethizole is a sulfonamide based antibiotic that exhibit bactericidal activities towards gram-negative bacteria. Sulfamehizole was shown to be effective in treating gram-negative Bacillus AmpC enzyme in elderly patients with lower respiratory tract infection and as well as against microbs responsible for tuberculosis.
References Mondelli, M., et al.: J. Molec. Struct., 1036, 180 (2013); Leelakrishnana, S., et al.: Adv. App. Sci. Res., 3, 3502 (2012); Ghoreishi, S.M., et al.: Anal. Lett., 46, 323 (2012);

• Brand: TRC

Chemical properties

• Molecular weight: 270.3313
• Formula: C₉H₁₀N₄O₂S₂
• Color/Form: White
• InChI: InChI=1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)
• InChI key: InChIKey=VACCAVUAMIDAGB-UHFFFAOYSA-N
• SMILES: Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1