Sumatriptan Succinate

CAS: 103628-48-4

Ref. TR-S810000

Product Information

• Name: Sumatriptan Succinate
• Synonyms: GR 43175C, Sumatriptan succinate (GR 43175C), Ph Eur Sumatriptan Impurity Mixture, GR 43175X, Sumatriptan Test Mix for Impurity Identification Solution 2, 1-[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]-N-methylmethanesulfonamide; butanedioic acid, 1H-Indole-5-methanesulfonamide, 3-[2-(dimethylamino)ethyl]-N-methyl-, butanedioate (1:1), 3-(2-(Dimethylamino)ethyl)-N-methylindole-5-methanesulfonamide succinate (1:1), Butanedioic acid, compd. with 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide (1:1), Gr 43175C, Imigran, Imigrane, Imiject, Imitrex, Megrelan, Migragesin, Sumagraine, Suminat, Sumitrex, Treximet

Description

Applications Sumatriptan Succinate is a selective 5-HT1B/1D-receptor agonist with anticonvulsant properties (1,2). Sumatriptan Succinate is used for migraine relief (2).
References (1) Razzaque, Z., et al.: Br J Clin Pharmacol. 47, 75 (1999) (2) Cady, R. K., et al.: J Headache Pain. 18, 17 (2017)

• Brand: TRC

Chemical properties

• Molecular weight: 413.49
• Formula: C₁₄H₂₁N₃O₂S·C₄H₆O₄
• Color/Form: White To Off-White
• InChI: InChI=1S/C14H21N3O2S.C4H6O4/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3, 1-2H2,(H,5,6)(H,7,8), 5-3(6)1-2-4(7)8/h4-5,8-9,15-16H,6-7,10H2,1-3H3
• InChI key: InChIKey=PORMUFZNYQJOEI-UHFFFAOYSA-N
• SMILES: CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1.O=C(O)CCC(=O)O