T-705RMP TEA Salt >80% (contain inorganics)

CAS: 356783-08-9

Ref. TR-T003205

Product Information

• Name: T-705RMP TEA Salt >80% (contain inorganics)
• Synonyms: T-705RMP TEA Salt, 6-Fluoro-3,4-dihydro-3-oxo-4-(5-O-phosphono-beta-D-ribofuranosyl)-Pyrazinecarboxamide TEA Salt, T 705RMP TEA Salt

Description

Applications T-705RMP TEA Salt is a metabolite of T-705RMP (CAS# 356783-08-9), which is a reagent used for the preparation of pyrazine-ribofuranose derivatives as antiviral agents that are useful in the treatment of viral infections. T-705 (Favipiravir) [F103350] gets converted to T-705RMP by host cells, but T-705RMP has little inhibitory effect on the replication of the host cells based on biological studies.
References Zhong, B., et al.: Faming Zhuanli Shenqing, 2014:924257 (2014); Yousuke, F., et al.: Antimicrob Agent Chemother., 49, 981 (2005)

• Brand: TRC

Chemical properties

• Molecular weight: 369.20 + x(101.19)
• Formula: C₁₀H₁₃FN₃O₉P·xC₆H₁₅N
• Color/Form: Neat
• InChI: InChI=1S/C10H13FN3O9P/c11-4-1-14(9(18)5(13-4)8(12)17)10-7(16)6(15)3(23-10)2-22-24(19,20)21/h1,3,6-7,10,15-16H,2H2,(H2,12,17)(H2,19,20,21)/t3-,6-,7-,10-/m1/s1
• InChI key: InChIKey=RWCWUNIDADUVEZ-KAFVXXCXSA-N
• SMILES: NC(=O)c1nc(F)cn([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c1=O