(-)-Tabersonine-D2

CAS: 4429-63-4

Ref. TR-T003902

Product Information

• Name: (-)-Tabersonine-D2
• Synonyms: methyl (1R,12R,19S)-4,6-dideuterio-12-ethyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,9,13-pentaene-10-carboxylate, 1H-Indolizino[8,1-cd]carbazole, aspidospermidine-3-carboxylic acid deriv., 1H-Indolizino[8,1-cd]carbazole-5-carboxylic acid, 3a-ethyl-3a,4,6,11,12,13a-hexahydro-, methyl ester, Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-, methyl ester, (5alpha,12beta,19alpha)-, Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-, methyl ester, (5α,12R,19α)-, Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-, methyl ester, (5α,12β,19α)-, Methyl (5Alpha,12Beta,19Alpha)-2,3,6,7-Tetradehydroaspidospermidine-3-Carboxylate, Methyl (5Alpha,19Alpha)-2,3,6,7-Tetradehydroaspidospermidine-3-Carboxylate, Tabersonin

Description

Applications (-)-Tabersonine-D2 is an intermediate used in the synthesis of Apovincaminic Acid-d4 (A729252), which is the main labelled metabolite of Vinpocetine (V332502), a vasodilator cerebral.
References Miskolczi, P., et al.: Eur. J. Clin. Pharmacol., 33, 185 (1987), Kiss, B., et al.: Eur. J. Pharmacol., 209, 109 (1991), Stephenson, D., et al.: J. Neurosci., 15, 5263 (1995),

• Brand: TRC

Chemical properties

• Molecular weight: 338.44
• Formula: C₂₁D₂H₂₂N₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C21H24N2O2/c1-3-20-9-6-11-23-12-10-21(19(20)23)15-7-4-5-8-16(15)22-17(21)14(13-20)18(24)25-2/h4-9,19,22H,3,10-13H2,1-2H3/t19-,20-,21-/m0/s1/i4D,8D
• InChI key: InChIKey=FNGGIPWAZSFKCN-ZTUPZEBNSA-N
• SMILES: [2H]c1cc([2H])c2c(c1)[C@@]13CCN4CC=C[C@@](CC)(CC(C(=O)OC)=C1N2)[C@H]43