Estimated delivery in United States, on Monday 30 Dec 2024
Product Information
Name:
TAE 684
Controlled Product
Synonyms:
- 5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine
- AE 684
- NVP-TAE 684
- NVT TAE-684
- 2,4-Pyrimidinediamine, 5-chloro-N<sup>2</sup>-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N<sup>4</sup>-[2-[(1-methylethyl)sulfonyl]phenyl]-
- 5-Chloro-N<sup>2</sup>-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N<sup>4</sup>-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine
- Ae 684
- Nvp-Tae 684
- Nvp-Tae684-Tae 684
- Nvt Tae-684
- See more synonyms
- Tae 684
- Tae684(Nvp-Tae684)
Description:
Applications TAE 684 is a potent, selective, and efficacious inhibitor of NPM-ALK, a fusion protein that is a key regulator of oncogenic events that drives the survival and proliferation of anaplastic large-cell lymphomas. Potent ALK inhibitor
References Schoenherr, C., et al.: Oncogene., 31, 5193 (2012); Tanizaki, J., et al.: Clin. Cancer. Res., 18, 6219 (2012); Heuckmann, J.M., et al.: Clin. Cancer. Res., 18, 4682 (2012);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
614.20
Formula:
C30H40ClN7O3S
Color/Form:
Neat
InChI:
InChI=1S/C30H40ClN7O3S/c1-21(2)42(39,40)28-8-6-5-7-26(28)33-29-24(31)20-32-30(35-29)34-25-10-9-23(19-27(25)41-4)37-13-11-22(12-14-37)38-17-15-36(3)16-18-38/h5-10,19-22H,11-18H2,1-4H3,(H2,32,33,34,35)
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Technical inquiry about: TR-T004600 TAE 684
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