Taurochenodeoxycholic Acid Sodium Salt

CAS: 6009-98-9

Ref. TR-T008130

Product Information

• Name: Taurochenodeoxycholic Acid Sodium Salt
• Synonyms: Ethanesulfonic acid, 2-[[(3a,5ß,7a)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1), Ethanesulfonic acid, 2-[[(3a,5ß,7a)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-, monosodium salt (9CI), Taurine, N-(3a,7a-dihydroxy-5ß-cholan-24-oyl)-, monosodium salt (8CI), Taurochenodeoxycholic acid sodium salt (6CI), NSC 681055, Sodium taurochenodeoxycholate, Sodium taurochenodesoxycholate, Sodium 2-[(3,7-Dihydroxy-24-Oxocholan-24-Yl)Amino]Ethanesulfonate, Ethanesulfonic Acid, 2-[[(3Alpha,5Beta,7Alpha)-3,7-Dihydroxy-24-Oxocholan-24-Yl]Amino]-, Monosodium Salt

Description

Applications Taurochenodeoxycholic Acid Sodium Salt is a bile acid conjugate and metabolite Taurolithocholic Acid (T009100) with antiinflammatory activity. Taurochenodeoxycholic Acid has been shown to inhibit hepatocyte apoptosis through suppression of Bid translocation to mitochondria.
References Emerman, S. et al.: J. Biol. Chem., 242, 661 (1967); Takikawa, Y. et al.: Falk Symp., 120, 249 (2001); Li, P. et al.: Zhong. Shour. Xue., 28, 1317 (2008);

• Brand: TRC

Chemical properties

• Molecular weight: 521.69
• Formula: C₂₆H₄₄NO₆S·Na
• Color/Form: Off-White
• InChI: InChI=1S/C26H45NO6S.Na/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29;/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/q;+1/p-1/t16-,17+,18-,19-,20+,21+,22-,24+,25+,26-;/m1./s1
• SMILES: C[C@H](CCC([O-])=NCCS(=O)(=O)O)[C@H]1CC[C@H]2C3C(O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C.[Na+]