Taurolithocholic Acid Sulfate Disodium Salt

CAS: 64936-83-0

Ref. TR-T009115

Product Information

• Name: Taurolithocholic Acid Sulfate Disodium Salt
• Synonyms: 2-[[(3α,5β)-24-Oxo-3-(sulfooxy)cholan-24-yl]amino]ethanesulfonic Acid Disodium Salt, N-(3α-Hydroxy-5β-cholan-24-oyl)taurine Hydrogen Sulfate (Ester) Disodium Salt, 3α-Hydroxy-5β-cholanoyltaurine 3-Sulfate Disodium Salt, Sulfolithocholyltaurine Disodium Salt, Sulfotaurolithocholic Acid Disodium Salt, Taurolithocholic Acid 3-Sulfate Disodium Salt, Taurolithocholic Acid 3α-Sulfate Disodium Salt, Taurosulfolithocholic Acid Disodium Salt
• Brand: TRC
• Description: Stability HygroscopicApplications Disodium salt of Taurolithocholic Acid Sulfate, a metabolite of bile acids. Sulfation is a major metabolic pathway involved in the elimination and detoxification of bile acids (BAs).References Kawamata, Y., et al.: J. Biol. Chem., 278, 9435 (2003); Alnouti, Y., et al.: Toxicol. Sci., 108, 225 (2009); Griffiths, W., et al.: J. Lipid Res., 51, 23 (2010); Huang, J., et al.: Xenobiotica, 2010, 40, 184 (2010)

Chemical properties

• Molecular weight: 607.73
• Formula: C₂₆H₄₃NO₈S₂·2Na
• Color/Form: Neat
• InChI: InChI=1S/C26H45NO8S2.2Na/c1-17(4-9-24(28)27-14-15-36(29,30)31)21-7-8-22-20-6-5-18-16-19(35-37(32,33)34)10-12-25(18,2)23(20)11-13-26(21,22)3;;/h17-23H,4-16H2,1-3H3,(H,27,28)(H,29,30,31)(H,32,33,34);;/q;2*+1/p-2/t17-,18-,19-,20+,21-,22+,23+,25+,26-;;/m1../s1
• SMILES: C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](OS(=O)(=O)[O-])CC[C@]4(C)[C@H]3CC[C@@]21C.[Na+].[Na+]