Product Information
- (4R,5S,6S)-3-[[1-(4,5-Dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Tetrahydrate
- [4R-[4alpha,5beta,6beta(R*)]]-3-[[1-(4,5-Dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Tetrahydrate
- LJC 11036 Tetrahydrate
Stability Hygroscopic
Applications Tebipenem Tetrahydrate is the active metabolite of Tebipenem Pivoxil (T012900) and shows excellent bactericidal activity against β-lactamase-nonproducing, ampicillin-resistant isolates.
References Nakashima, M. et al.: Nip. Kag. Ryo. Gak., 57, 90 (2009); Kishii, K. etal.: Antimicrob. Agents Chemother., 54, 3970 (2010); Xu, Z., et al.: Yaoxue Xuebao, 48, 993 (2013); Hazra, S., et al.: Biochem., 53, 3671 (2014); Li, H., et al.: Int. J. Antimicrob. Ag., 43, 92 (2014)
Chemical properties
Technical inquiry about: TR-T012840 Tebipenem Tetrahydrate
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