Product Information
Name:Telatinib
Controlled Product
Synonyms:
- 4-[[[4-[(4-Chlorophenyl)amino]furo[2,3-d]pyridazin-7-yl]oxy]methyl]-N-methyl-2-pyridinecarboxamide
- Bay 57-9352
Brand:TRC
Description:Applications Telatinib small-molecule inhibitor of vascular endothelial growth factor receptors 2 and 3 (VEGFR-2/-3) and platelet-derived growth factor receptor β tyrosine kinases. Telatinib is used therapeutically in patients with advanced solid tumors.References Strumberg, D. et al.: Br. J. Cancer, 99, 1579 (2008); Steeghs, N. et al.: Invest. New Drugs, 29, 137 (2011); Mross, K. et al.: Vasc. Cell, 3, 16 (2011);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:409.826
Formula:C20H16ClN5O3
Color/Form:Neat
InChI:InChI=1S/C20H16ClN5O3/c1-22-19(27)16-10-12(6-8-23-16)11-29-20-17-15(7-9-28-17)18(25-26-20)24-14-4-2-13(21)3-5-14/h2-10H,11H2,1H3,(H,22,27)(H,24,25)
InChI key:InChIKey=QFCXANHHBCGMAS-UHFFFAOYSA-N
SMILES:CNC(=O)c1cc(COc2nnc(Nc3ccc(Cl)cc3)c3ccoc23)ccn1
Technical inquiry about: Telatinib
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